Archive for the 'Cancer / Oncology'

Stress fuels cancer spread by triggering master gene

A new study from the US published in the Journal of Clinical Investigation finds that activation of a master gene called ATF3 that is important for helping cells adapt to stress may be involved in helping breast, and possibly other cancers spread to other parts of the body (metastasis)...

New findings could lead to drugs that fight back when tumors don’t respond to treatment

Cancer drugs known as ErbB inhibitors have shown great success in treating many patients with lung, breast, colon and other types of cancer. However, ErbB drug resistance means that many other patients do not respond, and even among those who do, tumors commonly come back...

New treatment strategy for breast cancer spread to brain

A combination of two new therapies already in clinical trials for the treatment of primary malignant brain tumors may also be effective in the treatment of breast cancer that has spread to the brain, according to US researchers. The team, from the University of California Los Angeles, demonstrated their new approach, which combines immunotherapy with gene therapy, in mice...

Removal Of Tumor-Associated Immune Cell Protein Decreases Tumor Progression

The number of tumor-associated immune cells is correlated with poor prognosis in cancer patients. Reducing these cells in mouse models of breast cancer reduces tumor metastasis, indicating that tumor-immune interactions are critical for cancer progression...

Major Advancement In Understanding Tissue Development Has Important Implications For Cancer

Findings published in the Journal of Cell Science show how the protein EB2 is a key regulator of tube-like structures inside cells and critical for normal tissue development and function. The findings are an important step in the race to find cures for cancers including gut, breast and pancreatic cancer...