Whole-genome testing helps identify treatments for breast cancer

A study testing all the DNA in the genome of cancer cells - the first of its kind - has identified individuals that may benefit from new treatments currently being tested in clinical trials.Metastatic cancer - cancer that has spread from the region of the body where it first started, to other areas - is generally regarded as being incurable.

A model for studying cancer and immune diseases

The protein STAT1 is involved in defending the body against pathogens and for inhibiting tumour development. If the levels of the protein are out of balance, disease may result. Researchers at the University of Veterinary Medicine, Vienna have developed a mouse whose STAT1 levels can be modified at will, enabling the study of the involvement of STAT1 in various processes.

Insight into why cancer incidence increases with age

The accumulation of age-associated changes in a biochemical process that helps control genes may be responsible for some of the increased risk of cancer seen in older people, according to a National Institutes of Health study.Scientists have known for years that age is a leading risk factor for the development of many types of cancer, but why aging increases cancer risk remains unclear.

For older women with breast cancer, brachytherapy offers lower rate of breast preservation compared to standard radiation

When comparing treatments designed to enable long-term breast preservation for older women with invasive breast cancer, researchers found those treated with brachytherapy were at higher risk for a later mastectomy, compared to women treated with standard radiation therapy. The research was led by The University of Texas MD Anderson Cancer Center.

Virus engineered to attack triple negative breast cancer cells

Scientists have discovered a potential cure for one of the most aggressive and least treatable forms of breast cancer called "triple negative breast cancer." In laboratory experiments involving human cancer cells, scientists used a virus similar to the one that helped eradicate smallpox to coax cancer cells to produce a protein which makes them susceptible to radioactive iodine.

Extended outcomes from adjuvant accelerated partial breast irradiation show tumor control, breast cosmesis and minimal late toxicity

Long-term (five-year) outcomes of breast cancer patients receiving adjuvant accelerated partial breast irradiation (APBI) after breast-conserving surgery show excellent tumor control and breast cosmesis (cosmetic outcomes) with minimal late toxicity, according to a study published in the February 1, 2014 print edition of the International Journal of Radiation Oncology - Biology - Physics (Red...

In patients with invasive breast cancer, external beam radiation therapy reduces risk of subsequent mastectomy

Standard external beam radiation therapy (EBRT) provided a higher breast preservation rate than brachytherapy in women age 66 and older with invasive breast cancer, according to a study published in the February 1, 2014 print edition of the International Journal of Radiation Oncology - Biology - Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology...