Fungal disease attacked by breast cancer drug

Tamoxifen, a drug currently used to treat breast cancer, also kills a fungus that causes a deadly brain infection in immunocompromised patients. The findings, which could lead to new treatments for a disease that kills more HIV/AIDS patients than tuberculosis, appear in mBio®, the online open-access journal of the American Society for Microbiology (ASM.

Consensus guideline on margins for breast-conserving surgery with whole-breast irradiation issued by ASTRO and SSO

Guideline focused on reducing ipsilateral breast tumor recurrence in stages I and II invasive breast cancer The American Society for Radiation Oncology (ASTRO) and the Society of Surgical Oncology (SSO) are pleased to announce the publication of the consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer.

Young female smokers at higher risk of common breast cancer type

New research suggests that young women who currently smoke and who have smoked one pack of cigarettes a day for 10 years or more have a much higher risk for estrogen receptor-positive breast cancer - the most common form of the disease - compared with women who have smoked for a shorter period of time.This is according to a study recently published in the journal Cancer.

Whole-genome testing helps identify treatments for breast cancer

A study testing all the DNA in the genome of cancer cells - the first of its kind - has identified individuals that may benefit from new treatments currently being tested in clinical trials.Metastatic cancer - cancer that has spread from the region of the body where it first started, to other areas - is generally regarded as being incurable.

A model for studying cancer and immune diseases

The protein STAT1 is involved in defending the body against pathogens and for inhibiting tumour development. If the levels of the protein are out of balance, disease may result. Researchers at the University of Veterinary Medicine, Vienna have developed a mouse whose STAT1 levels can be modified at will, enabling the study of the involvement of STAT1 in various processes.