New microchip demonstrates how metastasis takes place

Nearly 70 percent of patients with advanced breast cancer experience skeletal metastasis, in which cancer cells migrate from a primary tumor into bone -- a painful development that can cause fractures and spinal compression. While scientists are attempting to better understand metastasis in general, not much is known about how and why certain cancers spread to specific organs, such as bone, liver, and lungs. Now researchers have developed a three-dimensional microfluidic platform that mimics the spread of breast cancer cells into a bonelike environment.
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New data contradict current recommendations for management of breast biopsy abnormalities

Contrary to existing understanding, long-term follow-up of patients with two types of breast tissue abnormalities suggests that both types of abnormalities have the same potential to progress to breast cancer, according to a study published. Findings from this study could improve clinical management of patients with breast tissue abnormalities.
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Improved ultrasound imaging provides an alternative way of visualizing tumors

While ultrasound provides a less expensive and radiation-free alternative to detecting and monitoring cancer compared to technologies such as X-rays, CT scans and MRIs, the lower clarity and resolution of ultrasound has limited its use in cancer treatment. Researchers have overcome this limitation by combining ultrasound with a contrast agent comprised of micro-sized bubbles that pair with an antibody produced at elevated levels by many cancers.
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